Wikipedia describes the Sam & Max series as: "...an American media franchise about Sam and Max, a pair of anthropomorphic vigilante private investigators. The characters, who occupy a universe that parodies American popular culture, were created by Steve Purcell in his youth, and later debuted in a 1987 comic book series. The characters have since been the subject of a graphic adventure video game developed by LucasArts, a television series produced for Fox in cooperation with Nelvana Limited, and a series of episodic adventure games developed by Telltale Games. In addition, a variety of machinima and a webcomic have been produced for the series."
...however, Wikipedia is like the Encyclopedia Galactica of the internet. Usually accurate (when finicky trolls don't get involved), but quite boring. And Sam & Max don't do boring!
Meet the Freelance Police!
This is Sam!
This is Max!